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Bystander Macrophage Apoptosis afterMycobacterium tuberculosisH37Ra Infection

22 Oct 2007

Abstract excerpt

Human macrophages infected with Mycobacterium tuberculosis may undergo apoptosis. Macrophage apoptosis contributes to the innate immune response against M. tuberculosis by containing and limiting the growth of mycobacteria and also by depriving the bacillus of its niche cell. Apoptosis of infected macrophages is well documented; however, bystander apoptosis of uninfected macrophages has not been described in the...

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PMID: 17954721
DOI: 10.1128/iai.00614-07

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