Article
Cytogenetic and molecular biological characterization of an adult medulloblastoma.
Cancer genetics and cytogenetics - 15 Oct 2007
Holland Heidrun, Koschny Ronald, Krupp Wolfgang, Meixensberger Jürgen, Bauer Manfred, Schober Ralf, Kirsten Holger, Ganten Tom M, Ahnert Peter
Abstract excerpt
Medulloblastoma is a malignant invasive embryonal tumor, occurring in children mainly. It is rare in adults (<1% of adult brain tumors), and so comprehensive cytogenetic and molecular biological data on adult medulloblastomas are very limited. Conventional therapies provide disappointing long-term disease control, and new therapeutic options are being tested. We performed comprehensive cytogenetic analyses of an...
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