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Article

Apoptosis precedes necrosis of dystrophin-deficient muscle

1 Jun 1995

Abstract excerpt

The current view that death of dystrophin-deficient muscle fibers is a necrotic process relies primarily upon the histological appearance of the tissue after the degenerative process is well advanced. Here, we tested this view by examining the possibility that apoptosis is a component of dystrophin-deficient muscle cell death. Three assays for apoptosis were employed in analyzing prenecrotic, peak necrotic and...

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PMID: 7673339
DOI: 10.1242/jcs.108.6.2197

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