Article
Genetic interactions between<i>Drosophila melanogaster</i>Atg1 and paxillin reveal a role for paxillin in autophagosome formation
1 Jan 2008
Abstract excerpt
Autophagy is a conserved cellular process of macromolecule recycling that involves vesicle-mediated degradation of cytoplasmic components. Autophagy plays essential roles in normal cell homeostasis and development, the response to stresses such as nutrient starvation, and contributes to disease processes including cancer and neurodegeneration. Although many of the autophagy components identified from genetic...
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