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Article

One multiplex control for 29 cystic fibrosis mutations.

Genetic testing - 1 Jan 2007

Lebo Roger V, Bixler Michelle, Galehouse Donna

Abstract excerpt

A simple approach is described to synthesize and clone an inexhaustible supply of any homozygous and/or heterozygous controls diluted with yeast genomic DNA to mimic human genome equivalents for use throughout the entire multiplex mutation assay. As a proof of principle, the 25 cystic fibrosis mutation panel selected by the American College of Medical Genetics and four additional mutant sequences were prepared as...

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Source

Identifiers

PMID: 17949287
DOI: 10.1089/gte.2007.9994

Genes

CFTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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