Article
On the genealogy of a duplicated microsatellite.
Genetics - 1 Dec 2007
Zhang Kangyu, Rosenberg Noah A
Abstract excerpt
When a microsatellite locus is duplicated in a diploid organism, a single pair of PCR primers may amplify as many as four distinct alleles. To study the evolution of a duplicated microsatellite, we consider a coalescent model with symmetric stepwise mutation. Conditional on the time of duplication and a mutation rate, both in a model of completely unlinked loci and in a model of completely linked loci, we compute...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
