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Article

Long microsatellite alleles in Drosophila melanogaster have a downward mutation bias and short persistence times, which cause their genome-wide underrepresentation.

Genetics - 1 Jul 2000

Harr B, Schlötterer C

Abstract excerpt

Microsatellites are short tandemly repeated DNA sequence motifs that are highly variable in most organisms. In contrast to mammals, long microsatellites (>15 repeats) are extremely rare in the Drosophila melanogaster genome. To investigate this paucity of long microsatellites in Drosophila, we studied 19 loci with exceptionally long microsatellite alleles. Inter- and intraspecific analysis showed that long...

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Identifiers

PMID: 10880482
DOI: 10.1093/genetics/155.3.1213
PMCID: PMC1461152

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Source receipt: pubmed, retrieved 7 Sept 2026.

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