Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Birth-Death Dynamics of Microsatellites: Mechanistic Insights from Orthologous Loci in Felidae.

Genes - 19 Sept 2025

Zhang Wenping, Zhang Mingchun, Liu Hao

Abstract excerpt

Background/Objectives: The mutational dynamics of microsatellites over deep evolutionary timescales are poorly understood. This study aims to elucidate the life history of trinucleotide microsatellites by tracing orthologous loci across divergent vertebrate lineages and characterizing their mutational pathways. Methods: We developed a bioinformatic framework for identifying orthologous microsatellite loci using...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Exons
Share to Genetic Loci
Share to Microsatellite Repeats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Phylogeny

Source

Open in PubMed Open full text

Identifiers

PMID: 41010060
DOI: 10.3390/genes16091115
PMCID: PMC12469459

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Birth-Death Dynamics of Microsatellites: Mechanistic Insights from Orthologous Loci in Felidae.PMID 41010060Read ↗

Microsatellite and trinucleotide-repeat evolution: evidence for mutational bias and different rates of evolution in different lineages.Semantic proximity Read ↗

Mutational dynamics of microsatellites.Semantic proximity Read ↗

The direction of microsatellite mutations is dependent upon allele length.Semantic proximity Read ↗

The rise, fall and renaissance of microsatellites in eukaryotic genomes.Semantic proximity Read ↗

Every microsatellite is different: Intrinsic DNA features dictate mutagenesis of common microsatellites present in the human genome.Semantic proximity Read ↗

Two distinct modes of microsatellite mutation processes: evidence from the complete genomic sequences of nine species.Semantic proximity Read ↗

Ancient and Modern Genomes Reveal Microsatellites Maintain a Dynamic Equilibrium Through Deep Time.Semantic proximity Read ↗

Evidence for widespread convergent evolution around human microsatellites.Semantic proximity Read ↗

Heterogeneous mutation processes in human microsatellite DNA sequences.Semantic proximity Read ↗

Microsatellite evolution in vertebrates: inference from AC dinucleotide repeats.Semantic proximity Read ↗

Evolutionary dynamics of microsatellite DNA.Semantic proximity Read ↗

Long microsatellite alleles in Drosophila melanogaster have a downward mutation bias and short persistence times, which cause their genome-wide underrepresentation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.