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Article

Identification of a novel VEGFR-3 missense mutation in a Chinese family with hereditary lymphedema type I.

Journal of genetics and genomics = Yi chuan xue bao - 1 Oct 2007

Yu Zhengya, Wang Jingjing, Peng Shuling, Dong Bing, Li Yang

Abstract excerpt

A novel mutation of vascular endothelial growth factor receptor gene (VEGFR-3), was identified in a four-generation Chinese family with hereditary lymphedema type I (HL-I). Genetic linkage analysis was performed on the known genetic locus for HL-I with a panel of polymorphic markers, and then mutations were screened out by direct sequencing. By genotyping, the family showed the linkage to HL-I locus on 5q35.3....

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Identifiers

PMID: 17945164
DOI: 10.1016/S1673-8527(07)60097-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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