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Article

A novel mutation in the conserved sequence of vascular endothelial growth factor receptor 3 leads to primary lymphoedema.

The Journal of international medical research - 1 Aug 2018

Dai Ting, Li Bohan, He Bo, Yan Liwei, Gu Liqiang, Liu Xiaolin, Qi Jian, Li Ping, Zhou Xiang

Abstract excerpt

Objective To investigate whether lymphoedema in a Chinese family showed the hereditary and clinical characteristics of Milroy disease, an autosomal dominant form of congenital lymphoedema, typically characterized by chronic lower limb tissue swelling due to abnormal lymphatic vasculature development, and to perform mutational analyses of vascular endothelial growth factor receptor ( VEGFR)3. Methods Individuals...

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Identifiers

PMID: 29896974
DOI: 10.1177/0300060518773264
PMCID: PMC6134653

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A novel mutation in the conserved sequence of vascular endothelial growth factor receptor 3 leads to primary lymphoedema.PMID 29896974Read ↗

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