Polymorphism of the oestrogen receptor beta gene (ESR2) is associated with susceptibility to Graves' disease.

doi:10.1111/j.1365-2265.2007.03060.x

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Article

Polymorphism of the oestrogen receptor beta gene (ESR2) is associated with susceptibility to Graves' disease.

Clinical endocrinology - 1 Mar 2008

Kisiel Bartłomiej, Bednarczuk Tomasz, Kostrzewa Grazyna, Kosińska Joanna, Miśkiewicz Piotr, Płazińska Maria Teresa, Bar-Andziak Ewa, Królicki Leszek, Krajewski Paweł, Płoski Rafał

Abstract excerpt

OBJECTIVE: To investigate whether a polymorphism in the ESR2 gene (rs4986938, previously associated with endometriosis, ovulatory dysfunction and premature onset of coronary heart disease) increases the risk of Graves' disease (GD). SUBJECTS AND DESIGN: A cohort of 375 GD patients (300 females and 75 males) and 1001 individuals representative of the background population of Poland (502 males and 499 females) were...

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Identifiers

PMID: 17941906
DOI: 10.1111/j.1365-2265.2007.03060.x

Genes

ESR2
CTLA4
PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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