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Inorganic Polyphosphate: Essential for Growth and Survival

3 Apr 2009

Abstract excerpt

Inorganic polyphosphate (Poly P) is a polymer of tens to hundreds of phosphate residues linked by "high-energy" phosphoanhydride bonds as in ATP. Found in abundance in all cells in nature, it is unique in its likely role in the origin and survival of species. Here, we present extensive evidence that the remarkable properties of Poly P as a polyanion have made it suited for a crucial role in the emergence of cells...

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PMID: 19344251
DOI: 10.1146/annurev.biochem.77.083007.093039

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