Article
Genetic polymorphisms of DNA repair gene: XRCC1 Pro206Pro and Gln632Gln in a Chinese Han population.
Biochemical genetics - 1 Dec 2007
Yin Jiaoyang, Qi Rong, Ma Yegang, Sun Zhongfu, Wang Huiwen
Abstract excerpt
DNA repair genes are increasingly studied because of their critical role in maintaining genome integrity. The base excision repair (BER) pathway is a DNA repair pathway that operates on small lesions, such as oxidized or reduced bases, fragmented or nonbulky adducts, or those produced by methylating agents. The XRCC1 polymorphic system is the key gene of the BER pathway. In this study, polymorphisms of XRCC1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
