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Article

Genetic variation of the FAT gene at 4q35 is associated with bipolar affective disorder.

Molecular psychiatry - 1 Mar 2008

Abou Jamra R, Becker T, Georgi A, Feulner T, Schumacher J, Stromaier J, Schirmbeck F, Schulze T G, Propping P, Rietschel M, Nöthen M M, Cichon S

Abstract excerpt

A recent study suggested that the cadherin gene FAT exerts an influence on susceptibility to bipolar affective disorder (BPAD). We aimed to replicate this finding in a German sample (425 BPAD I and 419 controls). In addition, we performed a comprehensive linkage disequilibrium mapping of the whole genomic region of FAT and the neighboring circadian gene MTNR1A (48 single nucleotide polymorphisms (SNPs) covering...

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Identifiers

PMID: 17938632
DOI: 10.1038/sj.mp.4002111

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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