Article
Hypoplastic left heart syndrome is heritable.
Journal of the American College of Cardiology - 16 Oct 2007
Hinton Robert B, Martin Lisa J, Tabangin Meredith E, Mazwi Mjaye L, Cripe Linda H, Benson D Woodrow
Abstract excerpt
OBJECTIVES: This study sought to determine the size of the genetic effect (heritability) in families identified by a hypoplastic left heart syndrome (HLHS) proband. BACKGROUND: Hypoplastic left heart syndrome is a severe form of cardiovascular malformation (CVM), and it remains a leading cause of infant mortality and childhood morbidity. Familial clustering of HLHS and bicuspid aortic valve (BAV) has been...
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