Article
The GTP-binding protein Septin 7 is critical for dendrite branching and dendritic-spine morphology.
Current biology : CB - 23 Oct 2007
Xie Yunli, Vessey John P, Konecna Anetta, Dahm Ralf, Macchi Paolo, Kiebler Michael A
Abstract excerpt
Septins, a highly conserved family of GTP-binding proteins, were originally identified in a genetic screen for S. cerevisiae mutants defective in cytokinesis [1, 2]. In yeast, septins maintain the compartmentalization of the yeast plasma membrane during cell division by forming rings at the cortex of the bud neck, and these rings establish a lateral diffusion barrier. In contrast, very little is known about the...
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