Article
Three-dimensional ultrastructure of the septin filament network in Saccharomyces cerevisiae.
Molecular biology of the cell - 1 Feb 2012
Bertin Aurélie, McMurray Michael A, Pierson Jason, Thai Luong, McDonald Kent L, Zehr Elena A, García Galo, Peters Peter, Thorner Jeremy, Nogales Eva
Abstract excerpt
Septins are conserved GTP-binding proteins involved in membrane compartmentalization and remodeling. In budding yeast, five mitotic septins localize at the bud neck, where the plasma membrane is enriched in phosphatidylinositol-4,5-bisphosphate (PtdIns4,5P(2)). We previously established the subunit organization within purified yeast septin complexes and how these hetero-octamers polymerize into filaments in...
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