Article
[Study on the association of cholesteryl ester transfer protein gene mutations with the susceptibility to coronary atherosclerotic heart disease].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Feb 2003
Zheng Ke-qin, Zhang Si-zhong, Zhang Ke-lan, Zhang Li, He Yong, Kong Xiang-dong, Sun Yan, Su Zhi-guang
Abstract excerpt
OBJECTIVE: To determine the frequencies of 4 mutations of cholesteryl ester transfer protein (CETP) gene in Chinese population and to investigate the association of the mutations with lipid metabolism and the susceptibility to coronary atherosclerotic heart disease (CHD). METHODS: The target fragments of CETP gene were amplified and analyzed by PCR-restriction fragment length polymorphism technique in 209...
Topics
- Aged
- Carrier Proteins
- China
- Cholesterol Ester Transfer Proteins
- Coronary Artery Disease
- DNA
- DNA Restriction Enzymes
- Female
- Gene Frequency
- Genetic Predisposition to Disease
