Article
Relationship between glial reaction to a stab wound and tumor development after receiving transplacental ethylnitrosourea in the rat.
Acta neuropathologica - 1 Jan 1991
Schiffer D, Giordana M T, Vigliani M C, Cavalla P
Abstract excerpt
Fisher 344 rats born from mothers treated with ethylnitrosourea (ENU) 50 mg/kg intravenously were injured at the 1st and 2nd month of extrauterine life by a transcranial stab. The wound affected cerebral cortex, white matter and basal ganglia. The animals were killed 15 and 45 days and 5 months a...
Topics
- Animals
- Brain
- Bromodeoxyuridine
- Ethylnitrosourea
- Female
- Injections
- Maternal-Fetal Exchange
- Neoplasms, Experimental
- Neuroglia
- Phenotype
- Pregnancy
- Rats
- Rats, Inbred F344