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Article

Strategies for identifying hereditary nonpolyposis colon cancer.

Seminars in oncology - 1 Oct 2007

Evans D Gareth, Walsh Sheila, Hill James, McMahon Raymond T

Abstract excerpt

Hereditary nonpolyposis colorectal cancer (HNPCC) is the term given to a predisposition syndrome caused by inherited mutations in one of at least five DNA mismatch repair (MMR) genes. Dominant mutations in these genes predispose individuals to a range of cancers in addition to the most frequent, colorectal cancer. Endometrial cancer is the most notable additional malignancy, followed by ovarian, gastric, upper...

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Identifiers

PMID: 17920896
DOI: 10.1053/j.seminoncol.2007.07.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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