Article
Characterization of HIV-1 isolates from antiretroviral drug-naive children in southern India.
AIDS research and human retroviruses - 1 Sept 2007
Soundararajan Lakshmi, Karunaianandham Ramesh, Jauvin Valerie, Schrive Marie Helene, Ramachandran Ranjani, Narayanan Paranji R, Fleury Herve J, Swaminathan Soumya
Abstract excerpt
Access to antiretroviral therapy has expanded in many developing countries, including India. The standard first-line regimens consist of a combination of two nucleoside reverse transcriptase inhibitors and a nonnucleoside reverse transcriptase inhibitor, in a fixed drug combination. Data regarding resistance to these drugs are scarce, especially in children. We evaluated the pattern of polymorphism and potential...
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