Article
Aging, graying and loss of melanocyte stem cells.
Stem cell reviews - 1 Jan 2007
Sarin Kavita Y, Artandi Steven E
Abstract excerpt
Hair graying is one of the prototypical signs of human aging. Maintenance of hair pigmentation is dependent on the presence and functionality of melanocytes, neural crest derived cells which synthesize pigment for growing hair. The melanocytes, themselves, are maintained by a small number of stem cells which reside in the bulge region of the hair follicle. The recent characterization of the melanocyte lineage...
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