Article
Does early colectomy increase desmoid risk in familial adenomatous polyposis?
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Oct 2007
Durno Carol, Monga Neerav, Bapat Bharati, Berk Theresa, Cohen Zane, Gallinger Steven
Abstract excerpt
BACKGROUND & AIMS: Desmoid tumors are non-metastasizing fibromatoses that occur in 10%-20% of subjects with familial adenomatous polyposis (FAP). Intra-abdominal desmoid tumors are a major cause of mortality in FAP. FAP-associated desmoid tumors are linked to trauma, particularly abdominal surgery, family history of desmoids, hormonal factors, and the location of the APC mutation. We hypothesized that...
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