Article
Desmoid tumour biology in patients with familial adenomatous polyposis coli.
The British journal of surgery - 1 Apr 2013
Schiessling S, Kihm M, Ganschow P, Kadmon G, Büchler M W, Kadmon M
Abstract excerpt
BACKGROUND: Familial adenomatous polyposis (FAP) is caused by mutations in the adenomatous polyposis coli (APC) gene. Desmoid tumours affect up to 26 per cent of patients and contribute significantly to death. This study aimed to assess the influence of sex and mutation site on desmoid tumour development and sex-specific genetic differences in patients with FAP with and without desmoid tumours. METHODS: Patients...
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