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Article

The role of human innate immune factors in nasal colonization by Staphylococcus aureus.

Microbes and infection - 1 Oct 2007

van Belkum Alex, Emonts Marieke, Wertheim Heiman, de Jongh Christa, Nouwen Jan, Bartels Hans, Cole Alexander, Cole Amy, Hermans Peter, Boelens Hélène, Toom Nicole Lemmens-den, Snijders Susan, Verbrugh Henri, van Leeuwen Willem

Abstract excerpt

Staphylococcus aureus colonization of the human nares predisposes to sometimes severe auto-infection. To investigate whether genetic polymorphism affects the S. aureus carriage status, sequence variation in alpha-defensin and beta-defensin, and mannose-binding lectin (MBL) genes were determined for a group of volunteers (n=109) with known S. aureus nasal carriage status. DEFA1/3 expression was measured in a...

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Source

Identifiers

PMID: 17913546
DOI: 10.1016/j.micinf.2007.08.003

Genes

DEFA1
DEFA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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