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Article

Germ line origin and somatic mutations determine the target tissues in systemic AL-amyloidosis.

PloS one - 3 Oct 2007

Enqvist Stina, Sletten Knut, Stevens Fred J, Hellman Ulf, Westermark Per

Abstract excerpt

BACKGROUND: Amyloid is insoluble aggregated proteins deposited in the extra cellular space. About 25 different proteins are known to form amyloid in vivo and are associated with severe diseases such as Alzheimer's disease, prion diseases and type-2 diabetes. Light chain (AL) -amyloidosis is unique among amyloid diseases in that the fibril protein, a monoclonal immunoglobulin light chain, varies between...

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Identifiers

PMID: 17912358
DOI: 10.1371/journal.pone.0000981
PMCID: PMC1989140

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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