Genotypic approaches to therapy in children: a national active surveillance network (GATC) to study the pharmacogenomics of severe adverse drug reactions in children.

doi:10.1196/annals.1423.020

Article

Genotypic approaches to therapy in children: a national active surveillance network (GATC) to study the pharmacogenomics of severe adverse drug reactions in children.

Annals of the New York Academy of Sciences - 1 Sept 2007

Ross Colin J D, Carleton Bruce, Warn Dana G, Stenton Sunita B, Rassekh Shahrad Rod, Hayden Michael R

Abstract excerpt

A striking failure of modern medicine is the debilitating and lethal consequences of adverse drug reactions (ADRs), which rank as one of the top 10 leading causes of death and illness in the developed world with direct medical costs of 137-177 billion annually US dollars in the USA. Although many factors influence the effect of medications (e.g., age, organ function, drug interactions), genetic factors account...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Genotypic approaches to therapy in children: a national active surveillance network (GATC) to study the pharmacogenomics of severe adverse drug reactions in children.

Abstract excerpt

Topics

Related research