Article
Cognitive impairment in familial ALS.
Neurology - 2 Oct 2007
Wheaton M W, Salamone A R, Mosnik D M, McDonald R O, Appel S H, Schmolck H I, Ringholz G M, Schulz P E
Abstract excerpt
BACKGROUND: ALS is a progressive neurodegenerative disorder that affects upper and lower motor neurons. Recent reports demonstrate cognitive impairment in patients with sporadic ALS (sALS). OBJECTIVE: To test whether patients with familial ALS (fALS) have cognitive impairment and whether it is of the same type and degree as observed in sporadic ALS. METHODS: Thirty-seven consecutive patients with fALS underwent...
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