Article
Identification of dioxygenases required for Aspergillus development. Studies of products, stereochemistry, and the reaction mechanism.
The Journal of biological chemistry - 30 Nov 2007
Garscha Ulrike, Jernerén Fredrik, Chung DaWoon, Keller Nancy P, Hamberg Mats, Oliw Ernst H
Abstract excerpt
Aspergillus sp. contain ppoA, ppoB, and ppoC genes, which code for fatty acid oxygenases with homology to fungal linoleate 7,8-diol synthases (7,8-LDS) and cyclooxygenases. Our objective was to identify these enzymes, as ppo gene replacements show critical developmental aberrancies in sporulation...
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