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Aspergillus Cyclooxygenase-Like Enzymes Are Associated with Prostaglandin Production and Virulence

23 Jul 2005

Abstract excerpt

Oxylipins comprise a family of oxygenated fatty acid-derived signaling molecules that initiate critical biological activities in animals, plants, and fungi. Mammalian oxylipins, including the prostaglandins (PGs), mediate many immune and inflammation responses in animals. PG production by pathogenic microbes is theorized to play a role in pathogenesis. We have genetically characterized three Aspergillus genes,...

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PMID: 16040966
DOI: 10.1128/iai.73.8.4548-4559.2005

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