Article
Fungal oxylipins direct programmed developmental switches in filamentous fungi.
Nature communications - 14 Oct 2020
Niu Mengyao, Steffan Breanne N, Fischer Gregory J, Venkatesh Nandhitha, Raffa Nicholas L, Wettstein Molly A, Bok Jin Woo, Greco Claudio, Zhao Can, Berthier Erwin, Oliw Ernst, Beebe David, Bromley Michael, Keller Nancy P
Abstract excerpt
Filamentous fungi differentiate along complex developmental programs directed by abiotic and biotic signals. Currently, intrinsic signals that govern fungal development remain largely unknown. Here we show that an endogenously produced and secreted fungal oxylipin, 5,8-diHODE, induces fungal cellular differentiation, including lateral branching in pathogenic Aspergillus fumigatus and Aspergillus flavus, and...
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