Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alpha-actinin-1 phosphorylation modulates pressure-induced colon cancer cell adhesion through regulation of focal adhesion kinase-Src interaction.

American journal of physiology. Cell physiology - 1 Dec 2007

Craig David H, Haimovich Beatrice, Basson Marc D

Abstract excerpt

Physical forces including pressure, strain, and shear can be converted into intracellular signals that regulate diverse aspects of cell biology. Exposure to increased extracellular pressure stimulates colon cancer cell adhesion by a beta(1)-integrin-dependent mechanism that requires an intact cyt...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actinin
Share to Caco-2 Cells
Share to Focal Adhesion Protein-Tyrosine Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HT29 Cells

Share to Integrin beta1

Share to Mechanotransduction, Cellular

Share to Pressure

Share to src-Family Kinases

Source

Identifiers

PMID: 17898132
DOI: 10.1152/ajpcell.00118.2007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17898132-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alpha-actinin-1 phosphorylation modulates pressure-induced colon cancer cell adhesion through regulation of focal adhesion kinase-Src interaction.PMID 17898132Read ↗

Repetitive deformation activates focal adhesion kinase and ERK mitogenic signals in human Caco-2 intestinal epithelial cells through Src and Rac1.Semantic proximity Read ↗

The effects of increased extracellular deformation, pressure, and integrin phosphorylation on fibroblast migration.Semantic proximity Read ↗

Downregulation of Rap1GAP in Human Tumor Cells Alters Cell/Matrix and Cell/Cell AdhesionSemantic proximity Read ↗

ILK mediates the effects of strain on intestinal epithelial wound closure.Semantic proximity Read ↗

Repetitive deformation activates Src-independent FAK-dependent ERK motogenic signals in human Caco-2 intestinal epithelial cells.Semantic proximity Read ↗

OipA plays a role in Helicobacter pylori-induced focal adhesion kinase activation and cytoskeletal re-organization.Semantic proximity Read ↗

PINCH-1 Is an Obligate Partner of Integrin-linked Kinase (ILK) Functioning in Cell Shape Modulation, Motility, and SurvivalSemantic proximity Read ↗

Activation of the FAK-src molecular scaffolds and p130Cas-JNK signaling cascades by α1-integrins during colon cancer cell invasionSemantic proximity Read ↗

Phosphorylation of actopaxin regulates cell spreading and migration.Semantic proximity Read ↗

α-Actinin-4 Is Essential for Maintaining the Spreading, Motility and Contractility of FibroblastsSemantic proximity Read ↗

P21-activated protein kinase 1 induces colorectal cancer metastasis involving ERK activation and phosphorylation of FAK at Ser-910.Semantic proximity Read ↗

Cofilin overexpression affects actin cytoskeleton organization and migration of human colon adenocarcinoma cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.