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Article

TC-99m MIBI SPECT imaging in patients with lung carcinoma: is it a functional probe of multidrug resistance genes?

Journal of computer assisted tomography - 1 Jan 2000

Ak Ilknur, Gülbaş Zafer, Ocak Suna, Kaya Eser, Alataş Füsun, Vardareli Erkan, Metintaş Muzaffer

Abstract excerpt

OBJECTIVE: Multidrug-resistance (MDR) phenotype concerns altered membrane transport that results in lower cell concentrations of cytotoxic drug in many cancer types, including lung cancer, and is related to the overexpression of a variety of proteins that act as adenosine triphosphate-dependent extrusion pumps. Tc-99m Sestamibi (MIBI) is a transport substrate for P-glycoprotein (Pgp) pump. In this study, we...

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Share to ATP Binding Cassette Transporter, Subfamily B, Member 1
Share to Drug Resistance, Multiple

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Multidrug Resistance-Associated Proteins

Share to Neoplasm Staging

Share to Radiopharmaceuticals

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to Statistics, Nonparametric

Share to Tomography, Emission-Computed, Single-Photon

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Identifiers

PMID: 17895794
DOI: 10.1097/RCT.0b013e318033dee0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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