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Article

Unraveling multistate unfolding of pig kidney fructose-1,6-bisphosphatase using single tryptophan mutants.

The FEBS journal - 1 Oct 2007

Ludwig Heide C, Pardo Fabian N, Asenjo Joel L, Maureira Marco A, Yañez Alejandro J, Slebe Juan C

Abstract excerpt

Pig kidney fructose-1,6-bisphosphatase is a homotetrameric enzyme which does not contain tryptophan. In a previous report the guanidine hydrochloride-induced unfolding of the enzyme has been described as a multistate process [Reyes, A. M., Ludwig, H. C., Yañez, A. J., Rodriguez, P. H and Slebe, J. C. (2003) Biochemistry 42, 6956-6964]. To monitor spectroscopically the unfolding transitions, four mutants were...

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PMID: 17894826
DOI: 10.1111/j.1742-4658.2007.06059.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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