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Article

An association screen of myelin-related genes implicates the chromosome 22q11 PIK4CA gene in schizophrenia.

Molecular psychiatry - 1 Nov 2008

Jungerius B J, Hoogendoorn M L C, Bakker S C, Van't Slot R, Bardoel A F, Ophoff R A, Wijmenga C, Kahn R S, Sinke R J

Abstract excerpt

Several lines of evidence, including expression analyses, brain imaging and genetic studies suggest that the integrity of myelin is disturbed in schizophrenia patients. In this study, we first reconstructed a pathway of 138 myelin-related genes, all involved in myelin structure, composition, development or maintenance. Then we performed a two-stage association analysis on these 138 genes using 771 single...

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Source

Identifiers

PMID: 17893707
DOI: 10.1038/sj.mp.4002080

Genes

ARHGEF10
FGF1
FGFR1
PSAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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