Article
Compromised outer membrane integrity in Vibrio cholerae Type II secretion mutants.
Journal of bacteriology - 1 Dec 2007
Sikora Aleksandra E, Lybarger Suzanne R, Sandkvist Maria
Abstract excerpt
The type II secretion (T2S) system of Vibrio cholerae is a multiprotein complex that spans the cell envelope and secretes proteins important for pathogenesis as well as survival in different environments. Here we report that, in addition to the loss of extracellular secretion, removal or inhibition of expression of the T2S genes, epsC-N, results in growth defects and a broad range of alterations in the outer...
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