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Article

TolC promotes ExPEC biofilm formation and curli production in response to medium osmolarity.

BioMed research international - 1 Jan 2014

Hou Bo, Meng Xian-Rong, Zhang Li-Yuan, Tan Chen, Jin Hui, Zhou Rui, Gao Jian-Feng, Wu Bin, Li Zi-Li, Liu Mei, Chen Huan-Chun, Bi Ding-Ren, Li Shao-Wen

Abstract excerpt

While a high osmolarity medium activates Cpx signaling and causes CpxR to repress csgD expression, and efflux protein TolC protein plays an important role in biofilm formation in Escherichia coli, whether TolC also responds to an osmolarity change to regulate biofilm formation in extraintestinal pathogenic E. coli (ExPEC) remains unknown. In this study, we constructed ΔtolC mutant and complement ExPEC strains to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25243151
DOI: 10.1155/2014/574274
PMCID: PMC4163439

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