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Article

Genome-Wide Assessment of Outer Membrane Vesicle Production in Escherichia coli.

PloS one - 1 Jan 2015

Kulp Adam J, Sun Bo, Ai Teresa, Manning Andrew J, Orench-Rivera Nichole, Schmid Amy K, Kuehn Meta J

Abstract excerpt

The production of outer membrane vesicles by Gram-negative bacteria has been well documented; however, the mechanism behind the biogenesis of these vesicles remains unclear. Here a high-throughput experimental method and systems-scale analysis was conducted to determine vesiculation values for the whole genome knockout library of Escherichia coli mutant strains (Keio collection). The resultant dataset...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26406465
DOI: 10.1371/journal.pone.0139200
PMCID: PMC4583269

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