Article
A promoter polymorphism of the alpha2-HS glycoprotein gene is associated with its transcriptional activity.
Diabetes research and clinical practice - 1 Jan 2008
Inoue Mari, Takata Hiroshi, Ikeda Yukio, Suehiro Tadashi, Inada Shojiro, Osaki Fumiaki, Arii Kaoru, Kumon Yoshitaka, Hashimoto Kozo
Abstract excerpt
alpha2-Heremans Schmid glycoprotein (AHSG), also designated fetuin-A, is an abundant plasma protein that is expressed in hepatocytes. AHSG/fetuin-A has diverse biological functions including regulation of calcium homeostasis and inhibition of insulin receptor tyrosine kinase activity. The aim of this study was to detect single nucleotide polymorphisms (SNPs) of the AHSG gene that can be involved in regulation of...
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