Article
AHSG gene variant is associated with leanness among Swedish men.
Human genetics - 1 Jun 2005
Lavebratt Catharina, Wahlqvist Sofia, Nordfors Louise, Hoffstedt Johan, Arner Peter
Abstract excerpt
Alpha(2) Heremans-Schmid glycoprotein (AHSG) is a plasma protein inhibiting the activity of the insulin receptor tyrosine kinase. Ahsg knock-out mice have increased insulin sensitivity and are resistant to diet-induced obesity. We hypothesized that functional variants of the AHSG gene segregating in the human population would reflect variation in body mass index (BMI). We genotyped 356 overweight or obese (BMI:...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
