Article
AHSG gene variation is not associated with regional body fat distribution--a magnetic resonance study.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association - 1 Sept 2009
Müssig K, Staiger H, Machicao F, Machann J, Hennige A M, Schick F, Claussen C D, Fritsche A, Häring H-U, Stefan N
Abstract excerpt
Obesity-resistance in AHSG-knockout mice indicate an important role of alpha2-Heremans-Schmid glycoprotein/fetuin-A (AHSG) in the development of obesity. We studied whether genetic variation within AHSG affects whole-body adiposity and regional fat distribution in humans. We genotyped 321 subjects at increased risk for type 2 diabetes for five single nucleotide polymorphisms (SNP) rs2248690, rs4831, rs2070635,...
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