Article
Increased risk of oral cancer in relation to common Indian mitochondrial polymorphisms and Autosomal GSTP1 locus.
Cancer - 1 Nov 2007
Datta Sayantan, Majumder Mousumi, Biswas Nidhan K, Sikdar Nilabja, Roy Bidyut
Abstract excerpt
BACKGROUND: Polymorphisms at mitochondrial (mt) loci could modulate the risk of diseases including cancers. Here the mtDNA polymorphisms at 12,308 nucleotide pairs (np), 11,467 np, 10,400 np, and 10,398 np were studied to examine the association with the risk of oral cancer and leukoplakia, alone and in combination with polymorphisms at the GST loci. METHODS: Polymorphisms at mt loci were screened in 310 cancer,...
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