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Article

ABCG2 overexpression in colon cancer cells resistant to SN38 and in irinotecan‐treated metastases

3 Feb 2004

Abstract excerpt

Overcoming drug resistance has become an important issue in cancer chemotherapy. Among all known mechanisms that confer resistance, active efflux of chemotherapeutic agents by proteins from the ATP-binding cassette family has been extensively reported. The aim of the present study was to determine the involvement of ABCG2 in resistance to SN38 (the active metabolite of irinotecan) in colorectal cancer. By...

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Identifiers

PMID: 15027118
DOI: 10.1002/ijc.20032

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Source receipt: pubmed, retrieved 7 Sept 2026.

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ABCG2 overexpression in colon cancer cells resistant to SN38 and in irinotecan‐treated metastasesPMID 15027118Read ↗

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