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Article

Identification of a new gene encoding EPSPs with high glyphosate resistance from the metagenomic library.

Current microbiology - 1 Oct 2007

Jin Dan, Lu Wei, Ping Shuzhen, Zhang Wei, Chen Jian, Dun Baoqing, Ma Ruiqiang, Zhao Zhonglin, Sha Jiying, Li Liang, Yang Zhirong, Chen Ming, Lin Min

Abstract excerpt

Glyphosate, a powerful nonselective herbicide, acts as an inhibitor of the activity of the enzyme 5-enoylpyruvylshikimate-3-phosphate synthase (EPSPS) encoded by the aroA gene involved in aromatic amino acid biosynthesis. An Escherichia coli mutant AKM4188 was constructed by insertion a kanamycin cassette within the aroA coding sequence. The mutant strain is an aromatic amino acids auxotroph and fails to grow on...

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PMID: 17882506
DOI: 10.1007/s00284-007-0268-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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