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Article

Actions and Mode of Actions of FGF19 Subfamily Members

1 Jan 2008

Abstract excerpt

Fibroblast growth factors (FGFs) are humoral factors with diverse biological functions. While most FGFs were shown to work as local factors regulating cell growth and differentiation, recent investigations indicated that FGF19 subfamily members, FGF15/19, FGF21 and FGF23 work as systemic factors. FGF15/19 produced by intestine inhibits bile acid synthesis and FGF21from liver is involved in carbohydrate and lipid...

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PMID: 17878606
DOI: 10.1507/endocrj.kr07e-002

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