Article
CD8+ CD28- T regulatory lymphocytes inhibiting T cell proliferative and cytotoxic functions infiltrate human cancers.
Journal of immunology (Baltimore, Md. : 1950) - 1 Oct 2007
Filaci Gilberto, Fenoglio Daniela, Fravega Marco, Ansaldo Gianluca, Borgonovo Giacomo, Traverso Paolo, Villaggio Barbara, Ferrera Alessandra, Kunkl Annalisa, Rizzi Marta, Ferrera Francesca, Balestra Piercesare, Ghio Massimo, Contini Paola, Setti Maurizio, Olive Daniel, Azzarone Bruno, Carmignani Giorgio, Ravetti Jean Louis, Torre Giancarlo, Indiveri Francesco
Abstract excerpt
Tumor growth is allowed by its ability to escape immune system surveillance. An important role in determining tumor evasion from immune control might be played by tumor-infiltrating regulatory lymphocytes. This study was aimed at characterizing phenotype and function of CD8+ CD28- T regulatory ce...
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