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Article

Induction of complement proteins in a mouse model for cerebral microvascular A beta deposition.

Journal of neuroinflammation - 18 Sept 2007

Fan Rong, DeFilippis Kelly, Van Nostrand William E

Abstract excerpt

The deposition of amyloid beta-protein (A beta) in cerebral vasculature, known as cerebral amyloid angiopathy (CAA), is a common pathological feature of Alzheimer's disease and related disorders. In familial forms of CAA single mutations in the A beta peptide have been linked to the increase of vascular A beta deposits accompanied by a strong localized activation of glial cells and elevated expression of...

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Identifiers

PMID: 17877807
DOI: 10.1186/1742-2094-4-22
PMCID: PMC2099424

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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