Article
Requirement for Candida albicans Sun41 in biofilm formation and virulence.
Eukaryotic cell - 1 Nov 2007
Norice Carmelle T, Smith Frank J, Solis Norma, Filler Scott G, Mitchell Aaron P
Abstract excerpt
The cell wall of Candida albicans lies at the crossroads of pathogenicity and therapeutics. It contributes to pathogenicity through adherence and invasion; it is the target of both chemical and immunological antifungal strategies. We have initiated a dissection of cell wall function through targeted insertional mutagenesis of cell wall-related genes. Among 25 such genes, we were unable to generate homozygous...
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