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Altered composition of the cumulus-oocyte complex matrix during in vitro maturation of oocytes

15 Sept 2007

Abstract excerpt

BACKGROUND: In vitro maturation (IVM) of mammalian oocytes has potential health benefits for patients undergoing assisted reproduction as an alternative to gonadotrophin treatment. This procedure is also useful for studying the process of oocyte and early embryo development. However, oocytes undergoing IVM have much lower competence than in vivo matured oocytes. Efforts to optimize IVM success have focused on...

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PMID: 17872911
DOI: 10.1093/humrep/dem277

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