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New hyaluronan-based biomatrix for 3-D follicle culture yields functionally competent oocytes

10 Oct 2022

Abstract excerpt

BACKGROUND: Encapsulation of follicles within a biomatrix is one approach to maintaining 3-D follicle architecture during culture. Hyaluronan is one component of the natural extracellular matrix (ECM) that provides support to cells in vivo. This report describes the application of a novel tyramine-linked hyaluronan for 3-D in vitro follicle culture and the production of developmentally competent metaphase II...

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PMID: 36217168
DOI: 10.1186/s12958-022-01019-9

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